This book addresses methodological elements of epidemiological research studies on maternal substance abuse in pregnancy. Talking about the existing sources of mistake and how they can produce incorrect conclusions, it examines various epidemiological strategies and assesses their strengths and weaknesses. These refer both to the recognition of results (with special emphasis on genetic malformations) and to the types of exposure (substance abuse). Even more, the book goes over the issue of confounding and how to handle it, and offers a basic introduction to data. Special situations, e.g. different kinds of adult direct exposure, are analyzed. The book talks about pharmacovigilance and the info problem, concluding with a short list of aspects to consider when one desires to examine a published paper in the field. The book is primarily meant for pharmacologists, gynecologists and obstetricians, it will benefit all physicians working in perinatal care.
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